Oxidative Medicine and Cellular Longevity / 2013 / Article / Tab 3

Review Article

Polyphenols: Multipotent Therapeutic Agents in Neurodegenerative Diseases

Table 3

Modulation of mitochondrial targets by polyphenols.

TargetPolyphenolEffectReferences

AP-1EGCGDownregulation[116]
Bad/BaxResveratrolDownregulation[112]
Ferulic acidDownregulation[124]
Bcl-2LuteinUpregulation[125]
BaicaleinUpregulation[126]
Cox-2LuteinDownregulation[125]
HesperidinDownregulation[127]
Hibiscus sabdariffa polyphenolsDownregulation[128]
GCLMChrysin, apigenin, luteolinUpregulation[129]
GCLCChrysin, apigenin, luteolinUpregulation[129]
GPXEGCGUpregulation[130]
Red wine polyphenolsUpregulation[131, 132]
3,3′,5,5′-tetra-t-butyl-biphenyl-4,4′-diolUpregulation[133]
HO-1Butein, apigeninUpregulation[129]
LuteolinUpregulation[134]
IFN-γQuercetinDownregulation[135]
JNKQuercetinDownregulation[135]
EGCGDownregulation[116]
Hibiscus sabdariffa polyphenolsDownregulation[128]
JUNQuercetinDownregulation[135]
SOD PhloridzinUpregulation[136]

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