Review Article

Polyphenols: Multipotent Therapeutic Agents in Neurodegenerative Diseases

Table 1

Neuroprotective signal transduction by polyphenols.

PathwayPolyphenolReferences

P13K/AkT pathwayResveratrol[99, 100]
Baicalein[97]
NFκB pathwayKaempferol, acacetin, apigenin, luteolin[101]
Soybean isoflavones[102]
Fisetin[94]
Resveratrol[103]
Baicalein[104]
Silymarin[105]
Tetrahydroxystilbene[58]
Quercetin[101, 106]
Catechin hydrate[94]
STAT pathwaySilymarin[105]
PPAR pathwayBaicalein[104]
Resveratrol[107]
Pterostilbene[108]
Nrf2/HO1/ARE pathwayEpicatechin[109]
Resveratrol[110]
HIF-1αXanthohumol[111]
Resveratrol[112]
MAPKFlavone glycoside[113]
Quercetin[114]