Research Article

Superacid-Induced Reactions of Nefopam

Table 1

Products and isolated yields from the reactions of nefopam 1 with nucleophiles in CF3SO3H or CF3CO2H.

EntryNucleophileProductIsolated Yield

1Benzene496818.table.002

2o-Xylene496818.table.003

31,2-Dimethoxy-benzene496818.table.004

4Benzo-12-crown-4496818.table.005

51,3-Dichloro-benzene496818.table.006