Research Article
Investigation of the Possible Correlation between Idiopathic Parkinson’s Disease and Diabetes Mellitus in Egyptian Patients: A Pilot Study
Table 1
Demographic data of the diabetic patients and controls.
| | | Control (n = 30) | SU (n = 30) | SU + Met (n = 30) | |
| | Age (years) | | Median (range) | 59.5 (53–80) | 59 (50–85) | 57.5 (52–90) | 0.771 | | Gender | | Female | 14 (46.7%) | 8 (26.7%) | 7 (23.3%) | 0.112 | | Male | 16 (53.3%) | 22 (73.3%) | 23 (76.7%) | | | Smoking history | | Nonsmoker | 24 (80.0%) | 17 (56.7%) | 16 (53.3%) | 0.0652 | | Smoker | 6 (20.0%) | 13 (43.3%) | 14 (46.7%) | | | Hypertension | | No | 22 (73.3%) | 11 (36.7%) | 19 (63.3%) | 0.012 | | Yes | 8 (26.7%) | 19 (63.3%) | 11 (36.7%) | | | HbA1c (%) | | Median (range) | 5.6 (5.0–6.4) | 7.2 (6.2–10.5) | 7.0 (6.0–10.7) | <0.0011 | | DM duration (years) | | Mean ± SD (range) | — | 11.50 ± 6.04 (5–20) | 12.83 ± 6.76 (2–25) | 0.4244 | | RBDSQ score | | Median (range) | 2 (0–7) | 5 (3–12) | 5.5 (0–12) | <0.0011 | | RBDSQ positive | | Negative | 26 (86.7%) | 13 (43.3%) | 13 (43.3%) | <0.0013 | | Positive | 4 (13.3%) | 17 (56.7%) | 17 (56.7%) | |
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1Kruskal–Wallis rank sum test; 2Pearson’s chi-square test; 3Fisher’s exact test for count data; 4Student's t-test. DM: diabetes mellitus; Met: metformin; RBDSQ: REM sleep Behavior Disorder Screening Questionnaire; SU: sulphonylurea.
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