Validation of an Individualized Measure of Quality of Life, Patient Generated Index, for Use with People with Parkinson’s Disease

Table 2

Demographic and clinical characteristics of the sample (n = 76).

Characteristics	Mean (SD) or N (%)
Age (y)	69.1 (9.5)
Women	31 (41%)
Years since diagnosis	6.0 (4.1)
Years since symptom onset	8.2 (5.1)
Tremor dominant/akinetic rigid	46 (71)/19 (29)
History of falls (none/rare/monthly)	41 (63)/16 (25)/8 (12)
Levodopa equivalent dose (mg/day)	770.4 (523.7)
Hoehn and Yahr stage (1–5)	2.3 (0.9)
Patient Generated Index (10–0)	4.2 (1.8)
Parkinson’s Disease Questionnaire-8 (0–100)	27 (14.2)
RAND-36 Physical Function Index (0–100)	63.9 (27.7)
Geriatric Depression Scale (0–8)	2.1 (2.4)
Perceived Deficits Questionnaire-20 (0–80)	25.8 (11.9)
Apathy Scale (0–42)	22.3 (3.9)

SD, standard deviation; N, number. N = 64; N = 70; N = 67; N = 66. Patient Generated Index: 0 is the worst QOL, and 10 is perfect QOL. Hoehn and Yahr Stages: 1—minimal or no functional disability; 2—symptoms, no impairment of balance; 3—mild to moderate disability, still physically independent; 4—severe disability but still able to walk and stand unassisted; 5—confined to bed or wheelchair unless aided. Parkinson’s Disease Questionnaire-8: lower is better; RAND-36 Physical Function Index: higher is better; Geriatric Depression Scale: higher is more depression; Perceived Deficits Questionnaire-20: higher is more deficits, ≥40 considered cognitively impaired; Apathy Scale: high is more apathy.