Electrophysiological Predictors of Clinical Outcome in Traumatic Neuropathies: A Multicenter Prospective Study

Table 3

Multiple regression analysis of clinical outcome.

	All subjects; OR (95% IC)	NS group; OR (95% IC)	S group; OR (95% IC)	BP lesion; OR (95% IC)	Nerve lesion; OR (95% IC)
Gender	1.29; (0.5–3.3)	2.02; (0.58–6.99)	0.48; (0.06–3.66)	1.42; (0.19–10.65)	1.12; (0.37–3.41)
Age	1.00; (0.98–1.03)	1.00; (0.98–1.04)	0.98; (0.94–1.03)	1.05; (0.99–1.11)	0.99; (0.96–1.02)
Dominant hemisphere	2.19; (0.57–8.47)	4.84; (0.50–47.01)	1.50; (0.17–12.07)	23.59; (0.77–720.51)	1.44; (0.32–6.5)
Surgery	0.27; (0.12–0.61)	—	—	(0.02–0.58)	0.56; (0.2–1.6)
Polytrauma	3.15; (1.27–7.83)	2.10; (0.60–7.37)	(1.48–47.69)	5.10; (0.44–59.63)	(1.47–10.99)
BP lesions	0.44; (0.06–3.14)	0.26; (0.03–2.18)	NA	—	0.54; (0.08–3.77)
Nerve lesions	1.69; (0.23–12.24)	0.43; (0.05–3.82)	NA	3.12; (0.24–40.05)	—
SNAP amp. increase	2.28; (0.96–5.43)	(1.14–16.69)	1.98; (0.43–9.06)	2.81; (0.62–12.77)	1.35; (0.43–4.27)
CMAP amp. increase	(1.61–8.76)	2.67; (0.91–7.85)	(1.2–43.87)	(1.64–56.75)	2.78; (0.94–8.17)
MVR improvement	0.79; (0.31–2.02)	1.14; (0.31–4.24)	0.43; (0.07–2.54)	4.92; (0.47–51.70)	0.41; (0.10–1.61)
Reinnervation MUAPs	2.04; (0.60–6.92)	3.33; (0.75–14.84)	1.01; (0.07–15.92)	7.92; (0.29–215.10)	2.15; (0.55–8.43)

Multiple regression analysis of clinical outcome measure (modified Rankin scale) improvement, as dependent variable. Predictive (independent) variables include gender, age, dominant hemisphere, surgery, polytrauma, BP (brachial plexus) lesions, nerve lesions, SNAP (sensory nerve action potential) amplitude increase, CMAP (compound muscle action potential) amplitude increase, MVR (maximal voluntary recruitment) improvement, and reinnervation MUAPs (motor unit action potentials).
NS: nonsurgical; S: surgical; OR: odds ratio; CI: confidence interval; NA: information not sufficient for reliable estimates; and amp.: amplitude. Statistical significance ( < 0.05).