Regional Differences in Susceptibility to Hypoxic-Ischemic Injury in the Preterm Brain: Exploring the Spectrum from White Matter Loss to Selective Grey Matter Injury in a Rat Model

Table 2

Summary and comparison of study animal characteristics: by analysis group.

Characteristics	Controls 𝑛=10	Grade 0 MBP Loss 𝑛=16	Grade 1 MBP Loss 𝑛=13	Grade 2 MBP Loss 𝑛=9	Grade 3 MBP Loss 𝑛=11
Postnatal day at study start/surgery	6	6	6	6	6
Postnatal day at sacrifice	9	9	9	9	9
Mean weight at PD 6, grams ± SEM	13.19±0.45	13.56±0.23	13.12±0.28	13.76±0.34	13.95±0.32
Mean weight at PD 9, grams ± SEM	19.53±0.63	19.68±0.28	19.03±0.34	19.67±0.36	20.11±0.32
Mean weight gain, grams ± SEM	6.34±0.33	6.12±0.13	5.91±0.20	5.91±0.21	6.16±0.20
Surgery time, min ± SEM	N/A	8.06±0.74	8.08±0.94	9.56±0.60	9.45±0.86
Mean core temperature at surgery start, Celsius ± SEM	N/A	35.22±0.31	35.21±0.25	35.29±0.21	35.16±0.35
Mean core temperature at surgery end, Celsius ± SEM	N/A	32.77±0.36	31.82±0.45	31.99±0.17	32.05±0.24
Temperature decrease during surgery, Celsius ± SEM	N/A	2.45±0.27	3.39±0.54	3.36±0.23	3.11±0.36

SEM: standard error of mean.
PD: postnatal day.