A Controlled Clinical Study of Accelerated High-Dose Theta Burst Stimulation in Patients with Obsessive–Compulsive Disorder
Table 2
Outcome comparison between ahTBS and rTMS treatment groups.
Measures
ahTBS (n = 23)
rTMS (n = 22)
ANOVA time effect (p)
ANOVA group × time interaction
Pre-TMS
Post-TMS
Pre-TMS
Post-TMS
p
p
Symptom estimations
Y-BOCS total
23.13 (6.68)
13.96 (7.76)
25.41 (5.12)
18.68 (7.13)
<0.001
0.18a
Y-BOCS obsession
13.13 (2.62)
8.09 (3.85)
13.14 (2.93)
9.77 (3.59)
<0.001
0.10a
Y-BOCS compulsion
10.00 (5.40)
5.87 (5.10)
12.27 (3.56)
8.91 (4.39)
<0.001
0.47a
OCI-R
23.09 (14.53)
14.78 (13.02)
23.68 (11.77)
16.09 (8.85)
<0.001
0.78a
HAMD
8.22 (4.63)
4.87 (4.37)
7.59 (5.31)
4.36 (4.44)
<0.001
0.89a
HAMA
7.91 (5.61)
4.61 (4.91)
6.95 (5.10)
4.09 (3.92)
<0.001
0.62a
Neuropsychological tests
TMT (B-A)
49.89 (39.67)
43.37 (13.40)
39.6 (16.29)
36.43 (14.68)
0.29
0.72a
SCWT (CW-W)
12.69 (5.73)
7.83 (5.90)
11.12 (6.73)
8.26 (4.50)
<0.001
0.35b
DS forward
9.43 (1.65)
9.61 (1.73)
8.77 (0.97)
9.41 (1.10)
<0.001
0.09a
DS backward
6.52 (1.59)
6.83 (1.50)
6.73 (1.64)
7.59 (1.26)
<0.001
0.11a
Notes: Data are presented as mean (SD). Y-BOCS: Yale–Brown Obsessive–Compulsive Scale; HAMD: Hamilton Depression Scale; HAMA: Hamilton Anxiety Scale; OCI-R: obsessive–compulsive inventory-revised; TMT: trail making test; SCWT, Stroop color word test; DS: digit span. aRepeated the measurement of ANOVA. bOne patient in the ahTBS group did not take the test.
