Effect of Cathodal Transcranial Direct Current Stimulation for Lower Limb Subacute Stroke Rehabilitation
Table 2
The results of lower limb function (FMA-LE, 10MWT, TUGT, and Tinetti) and stroke scale assessment tests (HAMD and IADL).
Group
T0
T1
Effect size (95% CI)
T2
Effect size (95% CI)
Within-group comparisons
T1 vs. T0
T2 vs. T0
T1 vs. T2
value ()
value ()
value ()
FMA-LE
Trial
16.0 (14.00, 18.25)
21.50 (19.00, 23.00)
1.00 (0.00 to2.00)
24.00 (22.00, 26.00)
2.00 (1.00 to3.00)
(4.565)
(7.087)
(2.522)
Median (IQR)
Control
17.0 (15.50, 19.00)
20.00 (18.00, 21.50)
22.00 (20.00, 24.00)
(3.088)
(5.444)
(2.355)
10MWT (s)
Trial
17.25 (14.00, 19.50)
15.00 (13.50, 17.13)
-2.00 (-3.50 to -0.50)
14.00 (12.00, 16.13)
-1.00 (-3.00 to -0.00)
0.154 (1.626)
0.003 (2.800)
0.473 (1.173)
Median (IQR)
Control
17.5 (14.50, 24.00)
17.00 (15.00, 21.50)
16.0 (12.75, 20.50)
0.941 (1.068)
0.025 (2.824)
0.297 (1.755)
TUGT (s)
Trial
20.44 (3.82)
16.58 (2.35)
-1.48 (-2.93 to -0.02)
15.62 (2.42)
-1.30 (-2.56 to -0.04)
(3.836)
(4.820)
0.163 (0.957)
Mean (SD)
Control
20.11 (4.66)
18.06 (4.37)
16.92 (3.53)
0.067 (2.056)
0.001 (3.189)
0.613 (1.133)
Tinetti
Trial
14.0 (12.00, 17.00)
18.00 (16.00,21.00)
2.00 (0.00 to 3.00)
20.00 (18.00, 21.50)
1.00 (0.00 to 3.00)
(4.261)
(5.435)
0.250 (1.174)
Median (IQR)
Control
16.0 (13.00, 19.00)
17.00 (15.00, 20.00)
18.00 (16.00, 20.00)
0.120 (1.151)
(2.844)
0.209 (1.333)
IADL
Trial
13.0 (12.00, 15.25)
16.50 (15.00, 19.00)
2.00 (0.00 to 3.00)
18.50 (16.00, 20.00)
2.00 (0.00 to 3.00)
(2.913)
(4.130)
0.313 (1.217)
Median (IQR)
Control
13.0 (11.00, 18.00)
14.00 (12.00, 18.50)
16.00 (14.00, 18.00)
0.595 (1.089)
0.024 (2.267)
0.493 (1.178)
HAMD
Trial
7.46 (5.48)
7.13 (5.05)
0.55 (-1.33 to 2.43)
5.72 (3.54)
-1.15 (-2.74 to 0.45)
1.000 (0.326)
0.247 (1.739)
0.472 (1.413)
Mean (SD)
Control
7.29 (4.15)
6.58 (3.91)
6.87 (4.11)
1.000 (0.711)
1.000 (0.422)
1.000 (0.289)
Abbreviations: FMA-LE: Fugl-Meyer motor score of the lower extremity; 10MWT: 10-minute walk test; TUGT: timed up and walk test; Tinetti: Tinetti gait balance scale; IADL: instrumental ability to perform daily living score; HAMD: Hamilton depression scale; IQR: interquartile range; SD: standard deviation; CI: confidence interval. Statistically significant after Bonferroni’s correction ().
