The Long-Term Effects of Acupuncture on Hippocampal Functional Connectivity in aMCI with Hippocampal Atrophy: A Randomized Longitudinal fMRI Study

Table 2

Significant between-group differences in functional connectivity of the right hippocampus.

Contrast	Region	Cluster size (voxel)	MNI			value
				Rt. MTG/ITG	320		54	-12	-24	6.21
Lt. amygdala	188	-32		2	-18	4.45
Rt. fusiform	95	30		0	-48	4.39
	Lt. caudate	90	-2	6	6	4.25
	Rt. caudate	100	16	20	8	4.04
() > ()	Lt. MTG	71	-50	-18	-18	5.14
	Rt. ITG	66	54	-64	-12	4.86

Between-group results were thresholded at cluster-level (FDR corrected). The anatomical localization was implemented by using xjView software. HC: healthy control; aMCI: amnestic mild cognitive impairment; aMCI acupuncture1: aMCI acupuncture group at baseline; aMCI acupuncture2: aMCI acupuncture group at follow-up; aMCI control1: aMCI control group at baseline; aMCI control2: aMCI control group at follow-up; MNI: Montreal Neurological Institute; Lt.: left; Rt.: right; MTG: middle temporal gyrus; ITG: inferior temporal gyrus.