Review Article

Studying Cortical Plasticity in Ophthalmic and Neurological Disorders: From Stimulus-Driven to Cortical Circuitry Modeling Approaches

Figure 3

Mapping the uncertainty of model estimates: (a) maps obtained using conventional pRF mapping [3] and a custom implementation of the Monte Carlo Markov chain Bayesian pRF approach [50, 51]. Both methods result in similar visual field maps. However, the latter method also enables the estimation of the uncertainty associated with each parameter; (b) eccentricity, phase, and pRF size uncertainty maps obtained for the left hemisphere of a single healthy participant. The uncertainty maps describe how reliable each estimate is. For example, we see that the polar angle estimates for the central fovea (near fixation) are less reliable than those measured in the periphery. The uncertainty associated for each estimate was calculated as the difference between the 75% and 25% quantiles of the Bayesian Markov chain pRF distribution.
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