The Modulatory Effect of Cerebrovascular Burden in Response to Cognitive Stimulation in Healthy Ageing and Mild Cognitive Impairment

Table 5

Results of the independent-sample Mann-Whitney tests assessing the difference in cognitive change scores between high and low WML groups.

	Low WML			High WML			Median change scores		effect of WML on change scores
	Baseline (median)	Retest (median)		Baseline (median)	Retest (median)		Low WML	High WML
Healthy ageing
Token task	35.5	34.75	12	36	35.5	12	0	0	7.99
Raven’s progressive matrices	33	34	12	28.5	31.5	12	0.5	2	0.376
Rey figure—copy	34.5	36	12	33	34.5	12	0	1.5	0.32
Stroop—error interference	0	0	12	0	0	12	0	0	0.936
Corsi span	5	5	12	4.5	5	12	0	0	0.65
Digit span—forwards	6	6	12	6	6	12	0	0	0.503
Digit span—backwards	4.5	5.5	12	4	4	12	0	0.5	1
Naming task	20	20	12	20	20	12	0	0	0.538
MCI
Token task	33.5	32.5	11	34	33	10	0	0	0.847
Raven’s progressive matrices	24	22	11	27.5	28.5	10	-1	1	0.898
Rey figure—copy	29	28	11	29.25	31.25	10	0	1.75	0.171
Stroop—error interference	3	1.5	11	0.5	0	10	1	0	0.468
Corsi span	4	4	11	4	4	10	0	0	0.133
Digit span—forwards	5	6	11	6	6	10	0	0	0.519
Digit span—backwards	4	3	11	4	4	10	0	0	0.478
Naming task	19	20	11	18	19	10	1	0	0.949

Note: indicates significance when corrected for multiple comparisons (). Stroop—error interference: lower value indicates better performance.