Research Article

Abnormal Resting-State Functional Connectivity Strength in Mild Cognitive Impairment and Its Conversion to Alzheimer’s Disease

Table 2

Demographics and clinical characteristics of MCI-c and MCI-nc patients.

MCI-c ( = 21)MCI-nc ( = 10) or value value

Baseline
 Age (years)50–82 (68.6 ± 9.3)50–78 (66.5 ± 10.4) = 0.570.57
 Gender (M/F)11/103/7 = 4.190.24
 Education years4–20 (10.5 ± 4.6)0–21 (9.2 ± 5.9) = 0.660.52
 MMSE17–28 (23.5 ± 2.9)17–29 (23.6 ± 3.2) = −0.070.95
 MoCA9–24 (18.1 ± 3.7)10–24 (18.7 ± 4.5) = −0.360.73
 CDT0–3 (1.7 ± 0.9)1–3 (2.0 ± 0.7) = −0.790.44
 AVLT-I2–6.7 (4.4 ± 1.2)3–7 (4.9 ± 1.4) = −0.960.34
 AVLT-D0–6 (2.3 ± 1.9)0–7 (3.6 ± 2.6) = −1.600.12
 AVLT-R−3–13 (6.6 ± 4.2)1–12 (8.1 ± 3.1) = −0.990.33
Follow-up
 MMSE9–28 (20.0 ± 4.2)21–29 (24.4 ± 2.9) = −2.590.02
 MoCA4–22 (15.8 ± 4.3)12–24 (19.0 ± 4.0) = −1.690.10
 CDT0–3 (1.7 ± 0.9)1–3 (2.1 ± 0.7) = −1.230.23
 AVLT-I0.7–6 (4.1 ± 1.3)3.7–7.3 (5.5 ± 1.3) = −2.440.02
 AVLT-D0–8 (1.7 ± 2.3)0–6 (3.4 ± 2.0) = −1.990.06
 AVLT-R0–13 (6.1 ± 3.8)4–10 (8.3 ± 2.1) = −1.760.09

Data are presented as the range of minimum–maximum (mean ± SD).
MCI, mild cognitive impairment; MMSE, Mini-Mental State Examination; MoCA, Montreal Cognitive Assessment; CDT, clock drawing test; AVLT-I, auditory verbal learning test-immediate recall; AVLT-D, auditory verbal learning test-delayed recall; AVLT-R, auditory verbal learning test-recognition; MCI-c, mild cognitive impairment converter; MCI-nc, mild cognitive impairment nonconverter.
The value was obtained by two-tailed Pearson chi-square test.
The value was obtained by two-sample two-tailed -test.
MoCA included 15 MCI-c and 7 MCI-nc patients.
CDT included 19 MCI-c and 10 MCI-nc patients.
The follow-up clinical scores included 17 MCI-c and 7 MCI-nc patients.