Compensation through Functional Hyperconnectivity: A Longitudinal Connectome Assessment of Mild Traumatic Brain Injury

Figure 2

Functional connectivity (FC) was measured across the brain using the DICCCOL framework. (a), (b), and (c) show the optimized locations of DICCCOLs across the brain in the coronal, sagittal, and axial views, respectively. (d), (e), and (f) represent the time series allocated to three DICCCOLs obtained from the rsfMRI data of the gray matter of the 5 mm neighborhood of each DICCCOL. The Pearson correlation was calculated between time series of 358 DICCCOLs in order to obtain the FC of the brain at large scale. (g) and (h) show two examples of FC measurement, and (i) is a symmetric affinity matrix, which represents FC at a connectomic level.