Research Article

Motor Cortical Networks for Skilled Movements Have Dynamic Properties That Are Related to Accurate Reaching

Figure 4

Two representative examples of estimated GLM coefficients { 𝛼 𝑖 , 𝑘 } (shown in vertical axis, dimensionless) of cell pair interactions between unsuccessful and successful trials during reaching movement. Positive/negative coefficients represent excitatory/inhibitory effects. Notation 𝑐 𝑑 denotes the directional spiking dependence from trigger cell 𝑐 to target cell 𝑑 . The shaded areas around the curve indicate the 95% confidence intervals of the estimated coefficients. Only those coefficients whose 95% confidence intervals do not overlap with zero are identified as significant connections. In the two examples displayed (Dataset-1), the cells numbered 3, 8, and 9 were classified as two FS neurons and a RS neuron, respectively. (a) Estimated GLM coefficients using complete ( 2 1 + 2 1 ) trials. (b) Estimated coefficients averaged from 20 Monte Carlo runs using only half of ( 1 1 + 1 1 ) trials (shaded bars show the standard error of the mean). (c) Estimated GLM coefficients averaged from 100 Monte Carlo runs using shuffled successful/unsuccessful trial ID.
413543.fig.004a
(a)
413543.fig.004b
(b)
413543.fig.004c
(c)