Research Article

Adding to the Burden: Gastrointestinal Symptoms and Syndromes in Multiple Sclerosis

Table 3

Impact of reported affective spectrum disorder on MSIS score, gastrointestinal symptoms, and gastrointestinal syndromes.

Affective spectrum disorderNo affective spectrum disorderSignificance

95 (men = 16)123 (men = 32)Sex
MSIS—overall P < 0.01
 Physical
 Psychological P < 0.01
Globus25
Chest pain55
Heartburn1014
Dysphagia2112P = 0.02
Dyspepsia2313P = 0.012
Nausea115
Vomiting21N/D
Belching97
IBS2616P = 0.013
Constipation3842P = 0.45
Incontinence1419P = 0.96