Review Article

Evaluating the Use of Optical Coherence Tomography in Optic Neuritis

Figure 1

Case: A 26-year old woman with MS presented with a 2-month history of vision loss in both eyes. Best-corrected visual acuity was 20/150 in the right eye and count fingers (at 2 feet) in the left eye. There was a left relative afferent pupil defect. Fundus examination showed mild temporal pallor in the right (a) and left (b) eyes. Spectral domain OCT (c) showed that global average RNFL measurements were within normal limits in the right eye (OD) (87 μm) and the left eye (OS) (90 μm). There was relative temporal RNFL thinning in the left eye (arrow). Two and a half months later, the patient’s visual acuity improved to 20/20 in both eyes, albeit with mild residual color vision deficits. There was more obvious temporal pallor in the right (d) and left (e) eyes. Repeat SD-OCT testing (f) showed progressive global average RNFL atrophy in the right (OD) (76 μm) and left (OS) eyes (75 μm).
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(a) Right eye
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(b) Left eye
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(c) Spectral Domain OCT (SD-OCT)
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(d) Right eye
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(e) Left eye
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(f) Spectral Domain OCT