Clinical Study

Efficacy and Safety of Artesunate-Amodiaquine versus Artemether-Lumefantrine in the Treatment of Uncomplicated Plasmodium falciparum Malaria in Sentinel Sites across Côte d’Ivoire

Table 2

PCR-uncorrected and PCR-adjusted days 14 and 28 treatment outcomes according to study participant ages.

Age (year)ASAQ (%)AL (%)
[2–5[[5–15[[15–63]Total[2–5[[5–15[15–63Total

PCR-uncorrected day 14 cure rates
ACPR69/69 (100)57/57 (100)17/17 (100)143/143 (100)61/62 (98.4)73/73 (100)11/11 (100)145/146 (99.3)
ETF0/69 (0)0/57 (0)0/17 (0)0/143 (0)1/62 (1.6)0/73 (0)0/11 (0)1/146 (0.7)
LCF0/69 (0)0/57 (0)0/17 (0)0/143 (0)0/62 (0)0/73 (0)0/11 (0)0/146 (0)

PCR-uncorrected day 28 cure rates
ACPR68/69 (98.5)57/57 (100)17/17 (100)142/143 (99.3)59/62 (95.2)68/73 (93.2)11/11 (100)138/146 (94.5)
ETF0/69 (0)0/57 (0)0/17 (0)0/143 (0)1/62 (1.6)0/73 (0)0/11 (0)1/146 (0.7)
LCF1/69 (1.4)0/57 (0)0/17 (0)1/143 (0.7)2/62 (3.2)5/73 (6.8)0/11 (0)7/146 (4.8)

PCR-corrected day 28 cure rates
ACPR68/69 (98.6)57/57 (100)17/17 (100)142/143 (99.3)61/62 (98.4)73/73 (100)11/11 (100)145/146 (99.3)
ETF0/69 (0)0/57 (0)0/17 (0)0/143 (0)1/62 (1.6)0/73 (0)0/11 (0)1/146 (0.7)
LCF1/69 (1.4)0/57 (0)0/17 (0)1/143 (0.7)0/62 (0)0/73 (0)0/11 (0)0/146 (0)