Research Article
Formulation and Particle Size Reduction Improve Bioavailability of Poorly Water-Soluble Compounds with Antimalarial Activity
Table 4
Summary of orally dosed DQ distribution in the liver and in the blood.
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Data are derived from Table 3. DQ: decoquinate; PO: oral dose; AUC: area under the curve; : maximal concentration; DQ was orally dosed at 80 mg/kg for nanoparticle formulations and at 400 mg/kg for microsuspensions. |