Research Article
[Retracted] VGLL4 Protects against Oxidized-LDL-Induced Endothelial Cell Dysfunction and Inflammation by Activating Hippo-YAP/TEAD1 Signaling Pathway
Figure 6
The Hippo YAP/TEAD1 signaling pathway is involved in the protective mechanism of VGLL4 on HUVECs. The HUVECs were treated with Ox-LDL (100 μg/mL) for 24 h and transfected with pcDNA3.1-VGLL4, si-TEAD1, or si-YAP, respectively. (a) The cell viability in each group. (b) The apoptosis of HUVECs in each group. (c) The ROS level in each group. (d) The IL-6 level in each group. (e) The protein expression of VCAM-1 in each group. “” means compared with the control group at , and “#” means compared with the pcDNA3.1-VGLL4 group at . GAPDH was used as an invariant internal control for calculating protein fold changes.
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