A Metabolic Gene Signature to Predict Overall Survival in Head and Neck Squamous Cell Carcinoma

Table 3

Gene sets enriched in phenotype high and low.

Gene set name	Size	NES	NOM value
KEGG_GALACTOSE_METABOLISM	23	1.62	0.010
KEGG_NICOTINATE_AND_NICOTINAMIDE_METABOLISM	19	1.45	0.034
KEGG_RENAL_CELL_CARCINOMA	64	1.41	0.046
KEGG_PANTOTHENATE_AND_COA_BIOSYNTHESIS	16	1.59	0.031
KEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG	25	1.53	0.033
KEGG_BASE_EXCISION_REPAIR	33	-1.88	0.000
KEGG_SPLICEOSOME	109	-1.82	0.002
KEGG_HOMOLOGOUS_RECOMBINATION	24	-1.65	0.020
KEGG_NUCLEOTIDE_EXCISION_REPAIR	44	-1.64	0.022
KEGG_DNA_REPLICATION	36	-1.63	0.013

NES: normalized enrichment score; NOM: nominal; Gene sets with NOM value < 0.05 are considered as significant.