The Prognostic Impact of Circulating Regulatory T Lymphocytes on Mortality in Patients with Ischemic Heart Failure with Reduced Ejection Fraction

Table 3

Outcome analysis.

Cardiovascular mortality	Crude HR (95% CI)	value	Adjusted HR (95% CI)	value
Entire study cohort	0.53 (0.36-0.79)	0.002	0.60 (0.39-0.92)	0.017
Ischemic HFrEF	0.57 (0.35-0.91)	0.019	0.59 (0.36-0.96)	0.034
Nonischemic HFrEF	0.41 (0.12-1.44)	0.163	0.62 (0.17-2.31)	0.486

Cox proportional hazard model for % regulatory T cells within lymphocytes in patients with iHFrEF and niHFrEF. Hazard ratios (HR) for continuous variables refer to a 1-SD increase. The multivariate model was adjusted for age, gender, and NT-proBNP.