NPY Receptor 2 Mediates NPY Antidepressant Effect in the mPFC of LPS Rat by Suppressing NLRP3 Signaling Pathway

Figure 2

LPS group rats exhibited depressive-like behaviors in SPT and OFT compared with the CTL group. (a) The locomotion track of the CTL and LPS groups. The red area represented the longer residence of the rats, while the green area represents the shorter residence and the blue area represents the least residence of rats. (b, c) LPS group rats showed a lower activity score in OFT compared to the CTL group, horizontal activity score in OFT: , , ; vertical activity score in OFT: , , . (d) LPS group rats showed a decreased consumption of sucrose in SPT compared to the CTL group, , , . CTL: , LPS: . Values are expressed as . Independent -test results are shown in this figure.

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