Lepidium meyenii Walp Exhibits Anti-Inflammatory Activity against ConA-Induced Acute Hepatitis

Figure 4

Maca inhibits expression of proinflammatory cytokines in ConA-induced hepatitis. Blood and liver tissue samples were collected from the control, Maca-treated, ConA, and ConA + Maca groups at 8, 16, and 24 hours after ConA injection. (a–g) Serum concentration of TNF-α, IFN-γ, IL-1β, IL-2, IL-6, IL-12, and IL-17a and (h–l) liver tissue concentration of TNF-α, IFN-γ, IL-2, IL-6, and IL-12 were determined using CBA Flex Sets. The similar results are representative of three experiments. Data is expressed as the mean ± SD (). , , and vs. the ConA group. ConA, concanavalin A; Maca, Lepidium meyenii Walp; IFN-γ, interferon-γ; TNF-α, tumor necrosis factor alpha; IL-1β, interleukin-1β; IL-2, interleukin-2; IL-6, interleukin-6; IL-12, interleukin-12; IL-17a, interleukin-17a.

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