Research Article

Whole-Body Cryotherapy Decreases the Levels of Inflammatory, Oxidative Stress, and Atherosclerosis Plaque Markers in Male Patients with Active-Phase Ankylosing Spondylitis in the Absence of Classical Cardiovascular Risk Factors

Table 4

Activities of antioxidant enzymes (mean value ± standard deviation (SD)) in AS patients before and after the completion of a cycle of ten whole-body cryotherapy procedures with subsequent kinesiotherapy (WBC group) or a cycle of ten kinesiotherapy procedures only (KT group), with statistical analyses. (p): plasma; (e): erythrocyte lysates; Δ: difference prior to post treatment.

ParametersWBC groupKT group

Total SOD (p) (NU/ml)Before13.4 ± 2.1312.3 ± 1.850.145
After12.1 ± 1.881.7 ± 2.490.632
0.2330.301
Δ−1.28 ± 3.13−0.60 ± 2.650.512

SOD-Mn (p) (NU/ml)Before5.37 ± 2.754.56 ± 1.860.336
After6.27 ± 0.995.02 ± 1.640.015
0.1630.642
Δ0.90 ± 2.800.46 ± 2.460.642

SOD-CuZn (p) (NU/ml)Before8.09 ± 2.747.80 ± 2.210.749
After7.15 ± 1.327.05 ± 3.090.902
0.3260.063
Δ−0.93 ± 2.77−0.75 ± 2.720.854

Total SOD (e) (NU/mgHb)Before85.5 ± 17.3128.0 ± 11.2<0.001
After90.5 ± 11.9111.0 ± 15.6<0.001
0.4380.001
Δ5.02 ± 17.3−17.1 ± 11.8<0.001

CAT (e) (IU/mgHb)Before385.0 ± 70.3425.0 ± 53.60.084
After375.0 ± 58.3412.0 ± 58.60.088
0.5350.352
Δ−9.9 ± 57.0−13.0 ± 54.00.876

GPx (e) (IU/gHb)Before31.2 ± 4.9029.9 ± 2.840.363
After29.1 ± 2.9720.4 ± 5.05<0.001
0.0390.001
Δ−2.09 ± 3.61−9.49 ± 6.740.001

GR (e) (IU/gHb)Before1.72 ± 0.562.07 ± 0.520.043
After1.54 ± 0.601.65 ± 0.590.078
0.4690.002
Δ−0.18 ± 0.80−0.42 ± 0.410.622

: statistical significance of differences between both groups of patients; : statistical significance of differences between values before and after treatment in particular groups of subjects.