Research Article
Plasma Energy-Balance Metabolites Discriminate Asymptomatic Patients with Peripheral Artery Disease
Table 4
Metabolite concentrations in patients segregated according to the presence of hypertension.
| Metabolite | Hypertension | No | Yes |
| 3-hydroxybutirate | 0.21 (0.14–0.38) | 0.35 (0.14–0.42) | Aconitate | 4.59 (2.54–6.65) | 4.13 (2.60–6.60) | α-Ketoglutarate | 4.71 (2.81–6.67) | 3.70 (2.51–7.07) | Alanine | 213.5 (152.7–273.7) | 184.3 (137.3–255.1) | Aspartate | 181.6 (141.4–239.5) | 173.1 (137.3–200.4) | (Iso)citrate | 721.8 (566.6–934.0) | 654.2 (476.5–815.9) | Fumarate | 0.27 (0.19–0.40) | 0.22 (0.17–0.30)a | Glucose | 4955.9 (4459.1–5679.9) | 4418.1 (4134.8–5191.7)b | Glutamate | 1335.8 (725.0–2628.5) | 1786.6 (691.1–2891.7) | Glutamine | 5083.3 (2842.0–9072.2) | 4742.5 (1700.9–7003.8) | Isoleucine | 63.52 (52.24–75.19) | 57.88 (51.23–63.22)a | Lactate | 373.5 (308.3–452.5) | 332.3 (279.5–405.9)a | Leucine | 90.17 (71.33–109.35) | 84.54 (69.77–93.84) | Malate | 2.79 (1.96–4.09) | 2.23 (1.75–3.08)a | Pyruvate | 13.86 (3.85–24.11) | 8.78 (2.72–18.15)a | Serine | 135.3 (106.1–162.1) | 161.0 (103.6–172.0)a | Succinate | 9.15 (8.42–15.04) | 11.71 (8.49–15.47) | Succinyl-CoA | 11.21 (7.72–16.31) | 9.94 (7.52–14.25) | Valine | 107.3 (86.6–136.8) | 96.6 (78.8–134.8) |
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