Comparative Expression Analyses of Pro- versus Anti-Inflammatory Mediators within Synovium of Patients with Joint Trauma, Osteoarthritis, and Rheumatoid Arthritis

Figure 4

Detection of IL10 mRNA (a) and number of IL10-IR cells (b and c) in patients with joint trauma (JT), osteoarthritis (OA), and rheumatoid arthritis (RA). (a) Quantification of IL10 mRNA shows that IL10 mRNA was significantly higher in RA and OA compared to JT and control synovium (, one-way ANOVA followed by Tukey’s test). (b) Quantitative analysis of immunofluorescence microscopy for IL10-IR cells. ^∗Relative to control, ^#relative to other groups (, one-way ANOVA followed by Tukey’s test). Data are shown as means ± SEM. (c) 5-LOX-IR cells are more abundant in RA synovium than in JT, OA, and control synovium. Bar  =  20 μm.

(a)

(b)

(c)