Iron Reduces M1 Macrophage Polarization in RAW264.7 Macrophages Associated with Inhibition of STAT1

Figure 6

Effect of iron on M1 macrophages phagocytosis activity. RAW264.7 macrophages were polarized to an M1 phenotype in the absence (uns) or presence of 25 μg/mL of FAC, washed, and incubated with FITC-dextran at 37°C for 1 h; the intracellular FITC-dextran was measured by FACS. Data are mean ± SD for three independent experiments. (uns: unstimulated macrophages; , ).