Gene Expression, Oxidative Stress, and Senescence of Primary Coronary Endothelial Cells Exposed to Postprandial Serum of Healthy Adult and Elderly Volunteers after Oven-Cooked Meat Meals
Table 3
Enriched pathway-based sets identified by ConsensusPathDB.
Pathway name
Set size
Candidates contained
value
value
Pathway source
Chemical carcinogenesis
82
18 (22.0%)
0.000842
0.203
KEGG
MAPK signaling pathway
168
30 (17.9%)
0.000889
0.203
WikiPathways
Xenobiotics metabolism
53
13 (25.5%)
0.00101
0.203
EHMN
Drug metabolism
46
12 (26.1%)
0.00126
0.203
KEGG
TNFR1-induced NF-κB signaling pathway
26
8 (30.8%)
0.00263
0.232
Reactome
Oxidative stress-induced senescence
129
23 (18%)
0.0031
0.242
Reactome
Ubiquitin-mediated proteolysis
137
24 (17.5%)
0.00359
0.243
KEGG
Cellular senescence
192
30 (15.7%)
0.00654
0.318
Reactome
Oxidative stress
30
8 (26.7)
0.00693
0.318
WikiPathways
The fatty acid cycling model
5
3 (60%)
0.00812
0.318
Reactome
TNF signaling
37
9 (24.3%)
0.00816
0.318
Reactome
1243 genes (59.7%) from the input list (2877 genes) are present in at least one pathway.
