Effect of Previous High Glutamine Infusion on Inflammatory Mediators and Mortality in an Acute Pancreatitis Model

Figure 1

Median serum concentrations of interferon- (IFN-) gamma (a), interleukin- (IL-) 2 (b), IL-10 (c), and tumor necrosis factor- (TNF-) alpha (d) at 2, 12, and 24 h after acute pancreatitis induction with sodium taurocholate in Lewis rats previously treated or not treated with 48 h infusion of parenteral saline or glutamine. ≤ 0.050 versus 12 and 24 h; ≤ 0.050 versus 2 and 12 h; ≤ 0.050 versus 24 h; versus 2 and 12 h; = 0.060 versus 12 h.

(a)

(b)

(c)

(d)