Involvement of Angiopoietin-2 and Tie2 Receptor Phosphorylation in STEC-HUS Mediated by Escherichia coli O104:H4

Figure 2

Fluorescent immunocytochemistry microscopy images showing immunofluorescence staining for F-actin (red) and VE-cadherin (green) performed on 100% confluent P5 HMVECs. Cells were treated with 5% prefiltered human EDTA plasma. EDTA plasma samples were collected from healthy controls (a), patients with high Angpt-1 (Angpt-1: 15.5 and 17.2 ng/mL) (b), high Angpt-2 (Angpt-2: 13.6 and 15.6 ng/mL) (c), and both high Angpt-1 and Angpt-2 (Angpt-1: 12.1 and 10.1 ng/mL, Angpt-2: 9.3 and 12.9 ng/mL, resp.) (d).

(a)

(b)

(c)

(d)