Research Article

T, B, and NKT Cells in Systemic Inflammation in Obstructive Sleep Apnoea

Table 2

Proportion of lymphocyte subtypes and CD4+ : CD8+ ratio in the peripheral blood of patients with OSA and healthy subjects. Data expressed as median (p25–p75).

Lymphocyte subset (%)OSA ()Healthy subjects ()

B
CD19+
7.9
5.6–10.7
10.9
8.5–13.4
<0.05

T
CD 3+
74.4
67.0–80.0
71.7
67.8–77.2
NS

Th
CD4+
35.5
30.9–44.4
42.4
39.7–49.7
0.005

Tc
CD8+
36.4
28.1–45.1
26.8
23.1–38.7
0.02

Th : Tc0.9
0.6–1.5
1.5
1.2–1.9
0.0003

NK
CD3−CD16+/CD56+
15.5
11.5–24.3
8.5
6.9–14.6
<0.05

NKT-like
CD3+CD16+/CD56+
5.7
2.8–11.2
3.0
1.8–5.8
<0.05

CD3+/HLA DR+8.4
5.1–12.2
4.5
3.8–6.5
<0.05