Regulatory T Cells Protect Fine Particulate Matter-Induced Inflammatory Responses in Human Umbilical Vein Endothelial Cells
Figure 7
PDTC inhibits PM-induced inflammatory responses. HUVECs were pretreated for 30 min with the NF-κB inhibitor PDTC (10 μmol/L) before stimulation with PM (100 μg/mL) for 24 h. The adhesion molecules and inflammatory cytokines were detected by flow cytometry and Elisa. (a) Dot plots showing the percentages of VCAM-1 expression in HUVECs. (b) The VCAM-1 expression in different groups of HUVECs. (c) The concentration of sVCAM-1, sICAM-1, IL-6, and IL-8 in the supernatants from different groups of HUVECs. Data are expressed as means ± SEM of 5 independent experiments.
