The Protective Effect of Lidocaine on Septic Rats via the Inhibition of High Mobility Group Box 1 Expression and NF-B Activation
Figure 2
Lidocaine treatment improves the survival of CLP-induced septic rats. The seven-day survival rates were performed on rats treated with NS or lidocaine. Log-rank analysis demonstrated a significant improvement in survival for lidocaine 3, 6, and 9 mg/kg versus NS (; ; , ). NS: normal saline; Lido: lidocaine.
