Research Article
Inhibitory Effect of Natural Anti-Inflammatory Compounds on Cytokines Released by Chronic Venous Disease Patient-Derived Endothelial Cells
Table 2
Baseline release of cytokines/chemokines and growth factors by pathological VEC.
| Cytokines/Chemokines | Release levels (pg/mL/24 hours)a | Limit of detection (pg/mL) |
| MIP-1 | <OOR | 2.9 | IL-8 | 2,616 () | 0.4 | IL-7 | 11.6 () | 1.4 | IFN- | 2.1 () | 0.8 | IL-12 (p70) | 2.8 () | 0.6 | TNF- | 1.8 () | 0.7 | GM-CSF | 8.2 () | 7.5 | IFN-2 | 9.1 () | 2.9 | G-CSF | 49 () | 1.8 | IL-1RA | 10.4 () | 8.3 | MIP-1 | 4 () | 3.0 | VEGF | ND | 26.3 | EGF | ND | 2.8 | Eotaxin | 10.2 () | 4.0 | MCP-1 | 8,663 () | 1.9 | CXCL10 | 20.5 () | 8.6 | PDGF | 1,399 () | 2.2 | RANTES | 31 () | 1.2 |
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Values are expressed as median (mean ± SD); <OOR: out (below) of detection range; ND: not determinable because component of the endothelial medium.
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