Research Article

Interleukin-1β Accelerates the Onset of Stroke in Stroke-Prone Spontaneously Hypertensive Rats

Table 4

Effect of continuous IL-1β administration to SHRSP.

Before1 week

BW (g)Control249.3 ± 7.0276.7 ± 6.2
IL-1β248.4 ± 13.5263.2 ± 21.0
SBP (mmHg)Control202 ± 20203 ± 16
IL-1β200 ± 14199 ± 16
IL-1β (pg/mL)Control62.5 ± 29.256.1 ± 24.5
IL-1β62.6 ± 31.8112.2 ± 49.0*
Intake (g/day)Control23.2 ± 0.5
IL-1β17.9 ± 1.1***

Data presented as mean ± SD. Body weight (BW), systolic blood pressure (SBP), and plasma level of IL-1β were measured before (10 weeks of age) and 1 week after the initiation of IL-1β administration. Food intake (Intake) is presented as the mean weight of food eaten per day during the first week of IL-1β administration. * , *** versus Control. in each group.