Review Article

Sirtuin 1: A Dilemma in Transplantation

Figure 1

Schematic overview of human Sirt1–7 with a highly conserved catalytic core comprising NAD-dependent catalytic domain (NAD-binding pocket) (green) and zinc-binding domains (yellow). It also represents the amino acids (aa) number, molecular size (kDa), enzymatic activity, and intracellular localization of Sirt family.