Research Article

A Prognostic Tool for Individualized Prediction of Graft Failure Risk within Ten Years after Kidney Transplantation

Table 2

Joint latent class mixed model estimates of hazard ratio for graft failure risk.

Survival submodel
HR95% CIp-value

NDSA before transplantation (yes vs. no)3.27[1.75 - 6.13]<0.001
Proteinuria at M12 (>0.275 g/L vs. ≤0.275 g/L)2.41[1.22 - 4.76]0.011
dnDSA (yes vs. no)0.49[0.05 - 4.46]0.524
Acute rejection (yes vs. no)0.78[0.39 - 1.56]0.486
Interaction (dnDSAacute rejection)15.35[1.55 -152.43]0.019

HR= hazard ratio, CI= confidence interval, NDSA=non-donor-specific anti-HLA antibodies, and dnDSA=de novo donor-specific anti-HLA antibodies.