Research Article
Temporal Changes on the Risks and Complications of Posttransplantion Diabetes Mellitus Following Cardiac Transplantation
Table 2
Univariate and multivariate analysis for the risk factors related with the development of PTDM at 1 year.
| | Univariate analysis | Multivariate analysis | Parameters | Hazard Ratio [95% Confidence limits] | p value | Hazard Ratio [95% Confidence limits] | p value |
| Donor age | 1.017 [1.000, 1.034] | 0.0446 | | |
| Recipient age (+10 years) | 1.27 [1.025, 1.574] | 0.0292 | 1.302 [1.046, 1.621] | 0.0182 |
| Recipient BMI | 1.060 [1.000, 1.124] | 0.0510 | | |
| Hyperlipidaemia | 1.445 [0.921, 2.269] | 0.1094 | | |
| Cold ischemic time (+20 min) | 1.100 [1.009, 1.199] | 0.0303 | 1.110 [1.012, 1.216] | 0.0268 |
| Tacrolimus | 2.52 [1.57, 4.05] | <0.0001 | 3.378 [2.063, 5.530] | <0.0001 |
| Furosemide | 1.612 [0.959, 2.710] | 0.0714 | 2.048 [1.185, 3.541] | 0.0103 |
| Thiazide diuretics | 0.344 [0.084, 1.400] | 0.1362 | | |
| Year of transplant | | 0.0711 | | | 1983 to 1992 | 0.618 [0.357, 1.071] | 0.0863 | | | 1993 to 2002 | 0.549 [0.318, 0.945] | 0.0305 | | | 2003 to 2011 | - - - | - - - | | |
| Gender mismatch | | 0.1072 | | | No mismatch | - - - | - - - | | | Female recipient/Male | 0.342 [0.107, 1.091] | 0.0699 | | | donor | | | | | Male recipient/Female | 0.682 [0.375, 1.243] | 0.2116 | | | donor | | | | |
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