Pretransplant Factors and Associations with Postoperative Respiratory Failure, ICU Length of Stay, and Short-Term Survival after Liver Transplantation in a High MELD Population
Table 3
Univariate and multivariate analysis of ICU LOS.
ICU LOS > 3 days ( )
Univariate
Multivariate
Variable
β
OR
95% CI
β
OR
95% CI
Age at transplant > 65 years
−0.20
0.82
0.62
0.37–1.83
Inpatient status prior to transplant
0.65
1.95
0.04
0.100–4.04
−2.40
0.11
0.45
0.01–30.04
BMI > 30 kg/m2
0.01
1.01
0.77
0.95–1.07
Large volume ascites
0.20
1.22
0.66
0.50–2.94
Pretransplant MELD
0.22
1.25
<0.01
1.16–1.33
0.25
1.28
0.00
1.15–1.42
Preoperative respiratory failure
NA
NA
NA
NA
Smoking history positive
−0.12
0.89
0.73
0.46–1.73
Kidney transplant
0.03
1.03
0.97
0.30–3.51
Heart failure
0.34
1.41
0.06
0.99–2.00
1.43
4.16
0.34
0.23–76.36
Diastolic dysfunction
0.70
2.01
0.05
0.100–4.04
−2.49
0.08
0.40
0.01–28.04
Left ventricular EF < 50%
0.91
2.49
0.46
0.22–27.98
FEV1/FVC
0.61
1.83
0.39
0.47–7.20
FVC < 80%
0.69
2.62
0.05
1.01–6.79
−3.31
0.04
0.04
0.01–0.86
FEV1 < 80%
1.32
3.76
<0.01
1.46–9.70
3.61
36.88
0.02
1.89–719.14
Donor gender (male)
−0.25
0.78
0.45
0.41–1.48
Deceased (versus living) donor
0.67
1.95
0.07
0.96–3.96
0.53
1.70
0.37
0.54–5.41
Warm ischemic time > 40 minutes
−0.24
0.79
0.45
0.17–1.72
Cold ischemic time > 240 minutes
0.85
2.34
0.04
1.08–3.60
1.69
5.39
0.07
0.85–34.12
Recipient CMV IgG
−0.16
0.85
0.64
0.44–1.66
Packed red blood cell transfusion > 6 units
0.07
1.54
0.49
0.75–1.27
OR: odds ratio; 95% CI: 95% confidence interval; BMI: body mass index; MELD: Model for End Stage Liver Disease; EF: ejection fraction; FEV1: forced expiratory volume in one second; FVC: forced vital capacity; CMV: cytomegalovirus.