Pretransplant Factors and Associations with Postoperative Respiratory Failure, ICU Length of Stay, and Short-Term Survival after Liver Transplantation in a High MELD Population
Table 2
Univariate and multivariate analysis of PRF.
PRF ()
Univariate
Multivariate
Variable
β
OR
95% CI
β
OR
95% CI
Age at transplant > 65 years
−0.07
0.93
0.88
0.93–2.36
Inpatient status prior to transplant
0.05
1.09
0.88
0.41–2.39
BMI > 30 kg/m2
0.02
1.02
0.05
0.96–1.07
0.07
1.07
0.16
0.97–1.19
Large volume ascites
−0.19
0.83
0.72
0.29–2.38
Pretransplant MELD
0.16
1.18
<0.01
1.10–1.26
0.13
1.14
<0.01
1.03–1.25
Preoperative respiratory failure
2.42
11.28
<0.01
3.37–37.89
1.96
7.06
0.06
0.97–51.57
Smoking history positive
0.38
1.46
0.32
0.69–3.07
Kidney transplant
0.14
1.15
0.84
0.30–4.54
Heart failure
0.03
1.03
0.90
0.69–1.52
Diastolic dysfunction
0.04
1.04
0.92
0.47–2.31
Left ventricular EF < 50%
1.85
6.26
0.14
0.55–71.00
FEV1/FVC
−0.03
0.98
0.98
0.19–5.03
FVC < 80%
0.79
2.18
0.15
0.76–6.22
−0.33
0.72
0.64
0.18–2.91
FEV1 < 80%
1.03
2.08
0.35
1.04–7.44
Donor gender (male)
−0.02
0.98
0.95
0.47–2.04
Deceased (versus living) donor
0.14
1.15
0.75
0.51–2.57
Warm ischemic time > 40 minutes
−0.49
0.62
0.18
0.19–2.13
−0.06
0.94
0.93
0.22–4.03
Cold ischemic time > 240 minutes
1.33
3.77
0.02
1.35–6.37
0.82
2.28
0.26
0.55–9.40
Recipient CMV IgG
0.07
1.07
0.86
0.49–2.33
Packed red blood cell transfusion > 6 units
0.09
1.15
0.04
0.96–1.07
0.09
1.11
0.18
0.97–1.19
PRF: postoperative respiratory failure; ICU: intensive care unit; LOS: length of stay; SD: standard deviation; BMI: body mass index; MELD: Model for End Stage Liver Disease; EF: ejection fraction; FEV1: forced expiratory volume in one second; FVC: forced vital capacity; CMV: cytomegalovirus.