Clinical Study

The First Fifty ABO Blood Group Incompatible Kidney Transplantations: The Rotterdam Experience

Table 1

Clinical and demographic characteristics of patients receiving a blood type ABO-incompatible (ABOi) kidney transplant and matched ABO-compatible (ABOc) controls.

ABOiABOc value

Number of patients50100
Age recipient (median and range)54 years (22–75)55 years (19–77)n.s.*
Age donor (median and range)50 years (26–75)55.5 years (23–70)n.s.
Donor male : female ratio27 : 2358 : 42
Recipient male : female ratio32 : 1863 : 37
Previous transplantation (%)18%13%n.s.
Previous pregnancy (%)30%34%n.s.
Previous blood transfusion (%)20%24%n.s.
Preemptive transplantation10 (20%)10 (10%)n.s.
Number HLA MM (median)44n.s.
ABO blood group recipient (number and % of total)O 34 (68%)O 39 (39%)
A 8 (16%)A 45 (45%)
B 8 (16%)B 13 (13%)
AB 0 (0%)AB 3 (3%)
Percentage of patients with panel reactive antibodies >4%**10%4%n.s.

n.s.: not significant ( value > 0.05), most recent percentage of panel reactive antibodies positivity obtained before kidney transplantation. A PRA of <5% was considered as negative by the reference laboratory (Leiden, The Netherlands).