Review Article

Antibody-Mediated Rejection: An Evolving Entity in Heart Transplantation

Figure 1

Histopathologic and immunopathologic biopsy features of AMR. (a) A biopsy sample stained with hematoxylin and eosin shows evidence of endothelial cell swelling (arrow). (b) An immunoperoxidase stain shows diffuse C4d deposition in capillaries. (c) An immunoperoxidase stain confirms the presence of intravascular macrophages with positive staining for CD68.
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(a)
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(b)
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(c)