Review Article

Xenotransplantation of Embryonic Pig Kidney or Pancreas to Replace the Function of Mature Organs

Figure 3

Photomicrographs of mesenteric lymph node from an STZ-diabetic rhesus macaque, 78 days after transplantation of E28 pig pancreatic primordia. Sections (a), (c), and (e) are stained with an anti-insulin antibody. Sections (b), (e), and (f) are stained using a control serum. Sections of medullary sinus are delineated by arrows (a–d). Individual cells with beta cell morphology are delineated by arrowheads (e) and (f). Scale bars 120 um (a) and (b); 80 um (c) and (d); 20 um (e) and (f), reproduced with permission [11].
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