Differentiated thyroid cancer (DTC) is a generally indolent disease, although cases with certain clinicopathological features are progressive and life-threatening. Currently, the treatment strategies of DTC are quite uniform worldwide: total thyroidectomy, radioactive iodine (RAI) ablation, and thyroid-stimulating hormone (TSH) suppression. Such a stereotyped treatment might be easy for physicians, but it might be an overtreatment for many DTC patients without high-risk features and predicting an excellent prognosis. Recently, in some institutions, trials of observation and limited surgery for low-risk patients have been performed, and the dose of RAI for ablation came to be reduced for patients who were classified as low-risk based on clinicopathologic features. Unfortunately, comparable studies are very hard to perform, but therapeutic experience for low-risk DTC patients is now being accumulated in many institutions.

We invite papers demonstrating an experience of treatment for low-risk DTC patients in the fields of surgery, radiology, pathology, and endocrinology. Potential topics include, but are not limited to:

• Limited surgery for low-risk DTC: extent of thyroidectomy and prophylactic lymph node dissection
• Indication of completion total thyroidectomy for patients who underwent limited surgery under the diagnosis of adenomatous nodule or follicular tumor but were pathological diagnosed as follicular (or papillary) carcinoma
• Indication of postoperative RAI ablation for low-risk DTC patients: its necessity or unnecessity and dose of RAI
• Indication of TSH suppression therapy: its necessity or unnecessity and appropriate TSH levels
• Relationship between pathological examination and prognosis of low-risk DTC patients
• How to follow low-risk DTC patients after surgery (and RAI ablation): constant examination by specialist is necessary?

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