Prenatal Exposures to Multiple Thyroid Hormone Disruptors: Effects on Glucose and Lipid Metabolism

Figure 3

Placental transfer and biotransformation of TH-EDCs. Thyroid hormone endocrine disrupting chemicals (TH-EDCs) enter the placenta from the maternal compartment via various transporters located at the maternal interface of the placenta and are biotransformed by metabolizing enzymes to various metabolites that then enter the fetal compartment through transporters located at the fetal interface of the placenta. TR indicates transporters.