Review Article
TSH and Thyrotropic Agonists: Key Actors in Thyroid Homeostasis
Table 2
Constant parameters for diagnostic calculations.
| Symbol | Explanation | Value | Reference |
| | Correction coefficient for log-linear model | −0.1345 | [120] | | Dilution factor for T4 (reciprocal of apparent volume of distribution) | 0,1 L−1 | [11, 23] | | Clearance exponent for T4 | 1,1 * 10−6 sec−1 | [11, 23, 292] | | EC50 for TSH | 2,75 mU/L | [11, 23, 293] | | Dissociation constant T4-TBG | 2 * 1010 L/mol | [11, 23, 106] | | Dissociation constant T4-TBPA | 2 * 108 L/mol | [11, 23, 106] | | Dilution factor for T3 | 0,026 L−1 | [11, 23] | | Clearance exponent for T3 | 8 * 10−6 sec−1 | [11, 23] | | Dissociation constant of type 1 deiodinase | 5 * 10−7 mol/L | [11, 23, 294] | | Dissociation constant T3-TBG | 2 * 109 L/mol | [11, 23, 295] |
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