Vitamin D Deficiency in Dengue Hemorrhagic Fever and Dengue Shock Syndrome among Sri Lankan Children: A Case-Control Study
Table 2
Comparison of vitamin D-deficient (<20 ng/mL) and -nondeficient (≥20 ng/mL) groups among cases and controls.
Cases
value
Controls
value
25(OH)D < 20 ng/mL
25(OH)D ≥ 20 ng/mL
25(OH)D < 20 ng/mL
25(OH)D ≥ 20 ng/mL
Number
26
14
20
32
Age, yrs (mean, SD)
8.2 (2.9)
10.1 (2.3)
0.04
7.1 (3.7)
8.4 (3.7)
0.226
Sex (male), n (%)
14 (53.8)
8 (57.1)
0.55
9
16
0.726
25(OH)D (ng/mL), mean (SD)
15.4 (3.4)
28.4 (6.61)
<0.001
16.5
27.5
<0.001
WBC (109/L)
3.8 (1.6, 6.2)
3.2 (1.1, 6.5)
0.34
—
—
—
Platelets (109/L)
33 (10, 86)
37.5 (10, 90)
0.94
—
—
—
ALT (U/L)
42 (21, 475)
48.5 (14, 249)
0.88
—
—
—
AST (U/L)
113 (49, 409)
105 (42, 459)
0.52
—
—
—
DSS, n (%)
6 (23.7)
6 (42.9)
0.19
—
—
—
Blood transfused, n (%)
2 (7.7)
1 (7.1)
0.54
—
—
—
AST- aspartate aminotransferase, ALT- alanine aminotransferase, DSS- dengue shock syndrome, WBC- white cell count. Values are expressed as median (range) unless otherwise indicated. For comparisons, ANOVA, the chi-squared test, and the Mann–Whitney U test were used as appropriate.
