Immunological Consequences of Antihelminthic Treatment in Preschool Children Exposed to Urogenital Schistosome Infection
Table 2
Results from the non-parametric Wilcoxon signed-rank tests.
Antibody isotype
Treated group
Untreated group
CAP-IgM
−4.037 (<0.000)
−0.357 (0.36)
SWAP-IgM
−2.626 (0.0045)
−0.533 (0.297)
SEA-IgM
−0.987 (0.162)
−0.357 (0.361)
CAP-IgE
−0.683 (0.247)
−0.296 (0.383)
Antischistosome responses
SWAP-IgE
−2.633 (0.004)
−0.968 (0.166)
SEA-IgE
−2.747 (0.003)
−1.599 (0.055)
CAP-IgG4
−0.35 (0.363)
−0.106 (0.458)
SWAP-IgG4
−2.018 (0.022)
−0.415 (0.339)
SEA-IgG4
−0.718 (0.237)
−2.601 (0.003)
Antiallergen responses
Derp-IgG4
−3.746 (<0.000)
−1.96 (0.025)
Derp-IgE
−3.497 (<0.000)
−0.968 (0.166)
Schizont-IgM
−2.308 (0.01)
−1.992 (0.023)
Antiplasmodium responses
Schizont-IgG
−2.222 (0.013)
−0.734 (0.231)
CH150-IgG
−2.103 (0.018)
−1.473 (0.705)
MSP119-IgG
−2.043 (0.021)
−1.897 (0.029)
Dd2-IgG
−3.333 (0.0005)
−1.992 (0.023)
and values from the nonparametric Wilcoxon signed-rank tests comparing pre- and posttreatment antibody levels are shown for each antibody isotype. Significant results () are highlighted in bold and those significant after Bonferroni-adjustmentin italic font.CAP: cercariae antigen preparation, SWAP: soluble worm antigen preparation, and SEA: soluble egg antigen.
