An Assessment of the Genotoxicity and Subchronic Toxicity of a Supercritical Fluid Extract of the Aerial Parts of Hemp
Table 4
Summary table of the results for the mouse micronucleus test.
Groups (mg/kg bw)
Sampling time (hour)
Total number of PCEs analyzed
MPCE (per 4000 PCE)
PCE/NCE
Mean
±SD
Mean
±SD
Negative control 0
24
20000
4.40
1.14
1.13
0.04
500
24
20000
4.60
0.55
1.09
0.12
1000
24
20000
4.60
1.14
1.06
0.08
2000
24
20000
5.20
0.84
0.91
0.03
Positive control 60
24
20000
122.80∗∗
6.02
0.46
0.10
Negative control 0
48
20000
4.40
0.89
1.12
0.12
2000
48
20000
5.20
1.30
0.94
0.10
Positive control: cyclophosphamide. Negative control: 1% aqueous methylcellulose. ∗∗: to the concurrent negative control and to the historical control.
